Investigating heart function using large animal models

Core B - Large Animal Core

['FUNDING_P01'] · UNIVERSITY OF ALABAMA AT BIRMINGHAM · NIH-10897864

This study is looking at how the heart works in young and adult pigs to help find better treatments for heart conditions that could benefit patients like you.

Quick facts

Phase['FUNDING_P01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF ALABAMA AT BIRMINGHAM (nih funded)
Locations1 site (BIRMINGHAM, UNITED STATES)
Trial IDNIH-10897864 on ClinicalTrials.gov

What this research studies

This research focuses on understanding cardiac function through experiments conducted on neonatal and adult pigs. It utilizes advanced techniques such as magnetic resonance imaging (MRI) and electrophysiological evaluations to assess heart health and responses to treatments. The Large Animal Core provides a centralized facility for surgical procedures and cardiac assessments, ensuring high-quality data collection and analysis. Patients may benefit indirectly from the findings that could lead to improved treatments for heart conditions.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research are individuals with cardiac conditions, particularly those related to arrhythmias.

Not a fit: Patients without any cardiac issues or those who are not responsive to current heart treatments may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to breakthroughs in the treatment of cardiac arrhythmias and other heart-related conditions.

How similar studies have performed: Previous research using large animal models has shown promise in understanding cardiac function and developing new therapies, indicating a strong potential for success in this approach.

Where this research is happening

BIRMINGHAM, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.