Investigating heart function in women with severe pre-eclampsia during and after pregnancy
SHePREG: Study of Heart function in PRE-Eclampsia during and after PreGnancy
This study is looking at how severe pre-eclampsia affects heart health in women from different racial backgrounds, checking their heart function during delivery and again at 6 and 12 months after giving birth, to help find better ways to support women who might be at risk based on their genetics.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State Univ Hershey Med Ctr NIH-funded |
| Lab location | 1 site (Hershey, United States) |
| Project ID | NIH-11049303 on NIH RePORTER |
What this research studies
This research examines how severe pre-eclampsia affects heart function in women from various racial backgrounds, including Non-Hispanic Black, Non-Hispanic White, Hispanic, and South/Southeast Asian. The study will assess heart function at delivery and again at 6 and 12 months postpartum. By analyzing genetic profiles and potential heart dysfunction, the research aims to understand the long-term cardiac implications of pre-eclampsia. This could lead to tailored interventions for at-risk women based on their genetic backgrounds.
Who could benefit from this research
Good fit: Ideal candidates for this research are women who have experienced severe pre-eclampsia during pregnancy, particularly those from diverse racial backgrounds.
Not a fit: Patients who have not experienced pre-eclampsia or those with unrelated cardiac conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved monitoring and treatment strategies for women experiencing severe pre-eclampsia, ultimately reducing maternal cardiac complications.
How similar studies have performed: Previous research has shown that understanding genetic factors in cardiac conditions can lead to significant advancements in treatment, suggesting this approach has potential for success.
Where this research is happening
Hershey, United States
- Pennsylvania State Univ Hershey Med Ctr — Hershey, United States (Active)
Researchers
- Principal investigator: Bradley, Elisa Ann — Pennsylvania State Univ Hershey Med Ctr
- Study coordinator: Bradley, Elisa Ann
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.