Investigating heart failure with preserved ejection fraction

Mass General Brigham HeartShare Clinical Center

NIH-funded research Massachusetts General Hospital · NIH-10893036

This study is looking at heart failure with preserved ejection fraction (HFpEF) to find better treatments for patients like you, using advanced tests and data to understand the condition more clearly.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10893036 on NIH RePORTER

What this research studies

This research focuses on heart failure with preserved ejection fraction (HFpEF), a condition that affects many patients and is often difficult to treat. The team at Mass General Brigham is utilizing advanced clinical trials and comprehensive assessments, including cardiopulmonary exercise testing and advanced imaging techniques, to better understand HFpEF and identify effective therapeutic interventions. By analyzing data from electronic health records and conducting rigorous clinical trials, the research aims to clarify the best treatment pathways for patients suffering from this condition.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with heart failure with preserved ejection fraction or those experiencing significant breathlessness.

Not a fit: Patients with heart failure with reduced ejection fraction or those without any heart failure symptoms may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment options and better management strategies for patients with heart failure with preserved ejection fraction.

How similar studies have performed: Previous research has shown promise in understanding and treating heart failure, but this specific approach to HFpEF is still being explored and may offer novel insights.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.