Investigating heart failure in people with HIV
Immunologic, Inflammatory, and Clinical contributors to HIV-Related Heart Failure with Preserved Ejection Fraction (HFpEF)
This study is looking at how certain health factors affect heart failure in people living with HIV, with the hope of finding better ways to prevent and treat this condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University at Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-11012464 on NIH RePORTER |
What this research studies
This research aims to identify the clinical, immunologic, and inflammatory factors that contribute to heart failure with preserved ejection fraction (HFpEF) in individuals living with HIV. By analyzing a large cohort of over 35,000 patients, the study will link heart failure events to biological samples and patient-reported outcomes, enhancing our understanding of this serious condition. The goal is to improve screening, prevention, and treatment strategies for HFpEF among people with HIV, addressing a significant gap in current medical knowledge.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who are at risk for or diagnosed with heart failure.
Not a fit: Patients without HIV or those who do not have heart failure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better screening and treatment options for heart failure in patients with HIV, potentially improving their quality of life and survival rates.
How similar studies have performed: Previous research has indicated a higher prevalence of heart failure in HIV patients, suggesting that this approach could yield valuable insights into the condition.
Where this research is happening
Chicago, United States
- Northwestern University at Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Feinstein, Matthew Joel — Northwestern University at Chicago
- Study coordinator: Feinstein, Matthew Joel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.