Investigating heart failure in people living with HIV
Immunologic, Inflammatory, and Clinical contributors to HIV-Related Heart Failure with Preserved Ejection Fraction (HFpEF)
This study is looking at how certain health factors affect heart failure in people with HIV, aiming to improve ways to spot, prevent, and treat this serious condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University at Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-10770358 on NIH RePORTER |
What this research studies
This research aims to identify the clinical, immunologic, and inflammatory factors that contribute to heart failure with preserved ejection fraction (HFpEF) in individuals living with HIV. By analyzing a large cohort of over 35,000 patients, the study will link heart failure events to biological samples and patient-reported outcomes, providing a comprehensive understanding of the condition. The goal is to enhance screening, prevention, and treatment strategies for HFpEF in this population, addressing a significant health concern with high mortality rates.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who are at risk for or diagnosed with heart failure.
Not a fit: Patients who do not have HIV or those without any risk factors for heart failure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved screening and treatment options for heart failure in people living with HIV.
How similar studies have performed: Previous research has indicated a higher prevalence of heart failure in individuals with HIV, suggesting that this approach could yield valuable insights into the condition.
Where this research is happening
Chicago, United States
- Northwestern University at Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Feinstein, Matthew Joel — Northwestern University at Chicago
- Study coordinator: Feinstein, Matthew Joel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.