Investigating heart disease prevention in people living with HIV

1/2 REPRIEVE Extension for Trial Completion

NIH-funded research Massachusetts General Hospital · NIH-11086817

This study is looking at how statin medications might help people with HIV lower their risk of heart disease, and it's inviting a diverse group of participants to join in so we can learn more about keeping their hearts healthy.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11086817 on NIH RePORTER

What this research studies

This research focuses on understanding how statin therapy can help prevent cardiovascular disease (CVD) in individuals living with HIV. The ongoing REPRIEVE trial is examining the effects of statins on various risk factors associated with heart disease, aiming to provide valuable insights into effective prevention strategies. By enrolling a diverse group of participants from multiple countries, the study seeks to gather high-quality data that can inform future HIV care practices. Participants will undergo assessments to monitor their cardiovascular health and immune function over time.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living with HIV who are at risk for cardiovascular disease.

Not a fit: Patients who are not living with HIV or those who do not have risk factors for cardiovascular disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved heart disease prevention strategies for people living with HIV, ultimately enhancing their overall health and longevity.

How similar studies have performed: Previous research has shown promising results in using statins for cardiovascular risk reduction, making this approach both relevant and potentially impactful.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency SyndromeAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.