Investigating heart changes in childhood cancer survivors treated with anthracyclines
The Clinical Relevance of Anthracycline-Related Cardiac Remodeling in Childhood Cancer Survivors
This study is looking at how a common cancer treatment for kids might change the shape of the heart in childhood cancer survivors, with the goal of finding ways to keep their hearts healthy as they grow up.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10901989 on NIH RePORTER |
What this research studies
This research focuses on understanding how anthracycline chemotherapy, commonly used in pediatric cancer treatment, affects the heart's structure in childhood cancer survivors. The study aims to identify specific changes in the shape of the heart's left ventricle that may lead to heart dysfunction over time. By examining the relationship between these changes and factors like physical activity, the research seeks to develop targeted early treatment strategies to improve heart health in these survivors.
Who could benefit from this research
Good fit: Ideal candidates for this research are childhood cancer survivors who have received anthracycline treatment and are experiencing or at risk for cardiac issues.
Not a fit: Patients who have not received anthracycline treatment or those without a history of childhood cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved heart health management strategies for childhood cancer survivors, potentially reducing the risk of heart failure.
How similar studies have performed: Previous research has shown that early intervention in cardiac health can improve outcomes for patients with similar conditions, suggesting that this approach may be promising.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Narayan, Hari Kope — University of California, San Diego
- Study coordinator: Narayan, Hari Kope
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.