Investigating heart and lung health in patients with sleep apnea and COPD
Official title: The Left and Right Ventricles in Sleep Apnea with COPD
Funded at University of California, San Diego · NIH-10998265 · Data updated 2026-11-12
This study is looking at how having both obstructive sleep apnea and chronic obstructive pulmonary disease affects heart health, and it's for people who have either or both of these conditions to help find better ways to treat them.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | August 16, 2024 |
| Project end | August 15, 2027 |
| Funding year | 2024 |
| Award (this year) | $81,364 |
| NIH project number | 1F32HL176079-01 |
| Project ID | NIH-10998265 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults diagnosed with both obstructive sleep apnea and chronic obstructive pulmonary disease.
✕Less likely to help
Patients without a diagnosis of obstructive sleep apnea or chronic obstructive pulmonary disease may not benefit from this research.
What this research studies
This research focuses on understanding how obstructive sleep apnea (OSA) combined with chronic obstructive pulmonary disease (COPD), known as overlap syndrome (OVS), affects heart health. The study will use advanced cardiac MRI imaging to evaluate changes in the heart's structure and function in patients with OVS compared to those with only COPD or OSA. By exploring the mechanisms behind increased cardiovascular risks in these patients, the research aims to identify better treatment strategies. The principal investigator, Dr. Janna Raphelson, will also enhance her skills in biostatistics and trial design throughout this project.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options and better management of cardiovascular risks for patients with overlap syndrome.
How similar studies have gone: While there has been limited research specifically on overlap syndrome, similar studies have shown promising results in understanding cardiovascular risks in patients with sleep apnea and COPD separately.
Where this research is happening
-
University of California, San Diego
La Jolla, United States Active
Researchers
- Principal investigator: Raphelson, Janna — University of California, San Diego
- Study coordinator: Raphelson, Janna
Related research
Other NIH-funded projects on the same topics.
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Overlap of sleep apnea and COPD and its heart effects
This grant looks at how having both COPD and sleep apnea affects the heart and whether treating sleep apnea can improve heart risk in people with overlap syndrome.
-
Heart effects of having both sleep apnea and COPD
This research looks at how having both COPD and obstructive sleep apnea affects the heart and blood vessels in adults with these conditions.
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Investigating the heart risks of having both sleep apnea and COPD.
This study is looking at how having both chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) affects heart health, so if you have either condition or both, your participation could help us understand the risks and find better treatments.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.