Investigating heart and lung health in patients with sleep apnea and COPD
The Left and Right Ventricles in Sleep Apnea with COPD
This study is looking at how having both obstructive sleep apnea and chronic obstructive pulmonary disease affects heart health, and it's for people who have either or both of these conditions to help find better ways to treat them.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10998265 on NIH RePORTER |
What this research studies
This research focuses on understanding how obstructive sleep apnea (OSA) combined with chronic obstructive pulmonary disease (COPD), known as overlap syndrome (OVS), affects heart health. The study will use advanced cardiac MRI imaging to evaluate changes in the heart's structure and function in patients with OVS compared to those with only COPD or OSA. By exploring the mechanisms behind increased cardiovascular risks in these patients, the research aims to identify better treatment strategies. The principal investigator, Dr. Janna Raphelson, will also enhance her skills in biostatistics and trial design throughout this project.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with both obstructive sleep apnea and chronic obstructive pulmonary disease.
Not a fit: Patients without a diagnosis of obstructive sleep apnea or chronic obstructive pulmonary disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options and better management of cardiovascular risks for patients with overlap syndrome.
How similar studies have performed: While there has been limited research specifically on overlap syndrome, similar studies have shown promising results in understanding cardiovascular risks in patients with sleep apnea and COPD separately.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Raphelson, Janna — University of California, San Diego
- Study coordinator: Raphelson, Janna
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.