Investigating heart and brain function in survivors of Hodgkin Lymphoma
Cardiopulmonary function and cerebral blood flow in Hodgkin Lymphoma survivors
This study is looking at how treatments for Hodgkin Lymphoma might impact heart and lung health, and how that could affect brain function in survivors, so if you're a survivor, we’d love for you to join us to help understand these connections better!
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | St. Jude Children's Research Hospital NIH-funded |
| Lab location | 1 site (Memphis, United States) |
| Project ID | NIH-11009048 on NIH RePORTER |
What this research studies
This research focuses on understanding how treatments for Hodgkin Lymphoma can lead to complications in heart and lung function, which may affect brain health in survivors. The study will compare the cerebral blood flow and oxygen levels during exercise between Hodgkin Lymphoma survivors and healthy controls. Participants will undergo various tests, including pulmonary function tests and neurocognitive assessments, to explore the relationship between cardiopulmonary health and cognitive outcomes. The goal is to uncover the mechanisms linking cancer treatment to long-term health issues.
Who could benefit from this research
Good fit: Ideal candidates for this research are adult survivors of Hodgkin Lymphoma who have undergone treatment with bleomycin and/or radiation.
Not a fit: Patients who have not been treated for Hodgkin Lymphoma or those with other unrelated health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved monitoring and treatment strategies for Hodgkin Lymphoma survivors, enhancing their quality of life.
How similar studies have performed: Previous research has indicated that similar approaches to studying the long-term effects of cancer treatments on heart and brain function have shown promising results.
Where this research is happening
Memphis, United States
- St. Jude Children's Research Hospital — Memphis, United States (Active)
Researchers
- Principal investigator: Phillips, Nicholas S — St. Jude Children's Research Hospital
- Study coordinator: Phillips, Nicholas S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.