Investigating hearing problems related to myelination in Fragile X Syndrome

Myelination Deficits Underlying Auditory Issues in Fragile X Syndrome

NIH-funded research Oklahoma State University Stillwater · NIH-10201325

This study is looking at how problems with myelination, which is important for nerve function, affect how people with Fragile X Syndrome hear and process sounds, with the hope of finding ways to help improve their listening skills.

Quick facts

Grant typeR15 grant
Study typeNIH-funded research
Funding institutionOklahoma State University Stillwater NIH-funded
Lab location1 site (Stillwater, United States)
Project IDNIH-10201325 on NIH RePORTER

What this research studies

This research focuses on understanding how myelination deficits affect auditory processing in individuals with Fragile X Syndrome, a genetic condition associated with autism. The study examines the auditory brainstem circuit, which is crucial for processing sound information from both ears. By using various methods such as anatomical analysis, physiological recordings, and behavioral tests, the researchers aim to uncover the mechanisms behind these auditory issues. The findings could lead to better insights into how auditory processing can be improved in affected individuals.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with Fragile X Syndrome, particularly those experiencing auditory processing challenges.

Not a fit: Patients without Fragile X Syndrome or those not experiencing auditory issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved interventions for auditory processing difficulties in patients with Fragile X Syndrome.

How similar studies have performed: Previous research has shown promising results in understanding auditory processing deficits in autism, suggesting that this approach may yield valuable insights.

Where this research is happening

Stillwater, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.