Investigating gut bacteria in undernourished women and children in Bangladesh
The small intestinal microbiota in undernourished women and undernourished children in Bangladesh: identifying causal mechanisms and therapeutic targets
This study is looking at how the bacteria in our gut can impact growth in women and children in Bangladesh who are not getting enough nutrition, and it’s testing a special food that might help improve their health by supporting the right gut bacteria.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10868751 on NIH RePORTER |
What this research studies
This research focuses on understanding how the gut microbiota affects undernutrition in women and children in Bangladesh. By analyzing fecal samples from both healthy individuals and those suffering from moderate acute malnutrition, the study aims to identify the specific bacteria that contribute to growth issues. The researchers have developed a special food formulation that targets these gut bacteria, potentially leading to better growth outcomes. The study also explores the relationship between gut health and overall growth, particularly in the context of environmental factors.
Who could benefit from this research
Good fit: Ideal candidates for this research include undernourished women and children living in Bangladesh, particularly those experiencing moderate acute malnutrition.
Not a fit: Patients who are not undernourished or who do not reside in Bangladesh may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved nutritional interventions that significantly enhance growth and health in undernourished populations.
How similar studies have performed: Previous research has shown promising results in using microbiota-targeted interventions to improve nutritional outcomes, suggesting that this approach may be effective.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Gordon, Jeffrey I — Washington University
- Study coordinator: Gordon, Jeffrey I
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.