Investigating gut bacteria changes in anemic preterm infants
Study Gut Dysbiosis in Anemic Preterm Infants Using a Multiomics Approach
['FUNDING_R21'] · UNIVERSITY OF SOUTH FLORIDA · NIH-10725697
This study is looking at how severe anemia affects the gut bacteria in preterm babies, and it hopes to find out what level of anemia causes changes in their gut health, which could help doctors take better care of these little ones.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF SOUTH FLORIDA (nih funded) |
| Locations | 1 site (TAMPA, UNITED STATES) |
| Trial ID | NIH-10725697 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how severe anemia affects the gut microbiota in preterm infants. By analyzing stool samples and host responses over time, the study aims to identify the hematocrit threshold that leads to gut dysbiosis. The approach utilizes a multiomics strategy, integrating various biological data to provide insights into the relationship between anemia and gut health. This information could help improve clinical management and treatment strategies for anemia in vulnerable infants.
Who could benefit from this research
Good fit: Ideal candidates for this research are preterm infants, particularly those with very low birth weight or those at risk for developing anemia.
Not a fit: Patients who are not preterm infants or those who do not have anemia may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better management of anemia in preterm infants, potentially reducing complications and improving health outcomes.
How similar studies have performed: Previous research has indicated a link between anemia and gut dysbiosis in preterm infants, suggesting that this approach could yield valuable insights.
Where this research is happening
TAMPA, UNITED STATES
- UNIVERSITY OF SOUTH FLORIDA — TAMPA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HO, THAO — UNIVERSITY OF SOUTH FLORIDA
- Study coordinator: HO, THAO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.