Investigating gut bacteria changes in anemic preterm infants
Official title: Study Gut Dysbiosis in Anemic Preterm Infants Using a Multiomics Approach
Funded at University of South Florida · NIH-10725697 · Data updated 2026-11-12
This study is looking at how severe anemia affects the gut bacteria in preterm babies, and it hopes to find out what level of anemia causes changes in their gut health, which could help doctors take better care of these little ones.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of South Florida NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project start | September 11, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $412,500 |
| NIH project number | 1R21HD112776-01 |
| Project ID | NIH-10725697 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are preterm infants, particularly those with very low birth weight or those at risk for developing anemia.
✕Less likely to help
Patients who are not preterm infants or those who do not have anemia may not receive any benefit from this research.
What this research studies
This research focuses on understanding how severe anemia affects the gut microbiota in preterm infants. By analyzing stool samples and host responses over time, the study aims to identify the hematocrit threshold that leads to gut dysbiosis. The approach utilizes a multiomics strategy, integrating various biological data to provide insights into the relationship between anemia and gut health. This information could help improve clinical management and treatment strategies for anemia in vulnerable infants.
Why it matters
Potential benefit: If successful, this research could lead to better management of anemia in preterm infants, potentially reducing complications and improving health outcomes.
How similar studies have gone: Previous research has indicated a link between anemia and gut dysbiosis in preterm infants, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of South Florida
Tampa, United States Active
Researchers
- Principal investigator: Ho, Thao — University of South Florida
- Study coordinator: Ho, Thao
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.