Investigating glutamate receptors in neurological diseases
Glutamate receptors and human neurological disease
This study is looking at how certain brain receptors work and how changes in them might be linked to Alzheimer's disease, with the hope of finding new ways to tailor treatments for patients based on their unique genetic makeup.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11083576 on NIH RePORTER |
What this research studies
This research focuses on understanding how glutamate receptors function in the brain and their role in neurological diseases like Alzheimer's. By using advanced techniques such as electrophysiology and cryo-electron microscopy, researchers will explore how variations in these receptors can affect brain health. The study aims to identify genetic mutations that may contribute to disease risk and develop new therapeutic strategies to improve patient outcomes. Patients may benefit from insights that could lead to personalized treatment options based on their genetic profiles.
Who could benefit from this research
Good fit: Ideal candidates include individuals with genetic variations in glutamate receptor genes or those at risk for neurological diseases such as Alzheimer's.
Not a fit: Patients with neurological diseases not associated with glutamate receptor dysfunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that improve treatment for patients with neurological diseases.
How similar studies have performed: Previous research has shown promise in targeting glutamate receptors for therapeutic interventions in neurological diseases, indicating a potential for success in this approach.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Traynelis, Stephen F — Emory University
- Study coordinator: Traynelis, Stephen F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.