Investigating genetics and cognitive function in Mexican teachers.
Official title: Mexican Teachers Cohort Study: Genetics and Cognitive Function
Funded at Rush University Medical Center · NIH-10979739 · Data updated 2026-11-12
This study is looking at how genes might affect thinking and memory in older Mexican teachers, hoping to find new clues about why some people experience cognitive decline or Alzheimer's, and it's a chance for participants to help improve our understanding of brain health in Hispanic communities.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rush University Medical Center NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | September 30, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $2,724,178 |
| NIH project number | 1U01AG084547-01A1 |
| Project ID | NIH-10979739 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older Mexican women, particularly those who are teachers and may be at risk for cognitive decline.
✕Less likely to help
Patients who are younger than 65 or do not have a Hispanic background may not benefit from this research.
What this research studies
This research focuses on understanding the genetic factors that influence cognitive function among older Mexican teachers. By analyzing genetic data from nearly 20,000 participants, the study aims to identify novel genetic drivers of cognitive decline and Alzheimer's disease. The cohort consists of female teachers from diverse regions in Mexico, providing a unique perspective on health disparities in dementia. Participants will contribute their genetic information to a larger database, enhancing the understanding of how genetics affects cognitive health in Hispanic populations.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing and treating cognitive decline and Alzheimer's disease in older Hispanic individuals.
How similar studies have gone: Previous research has shown success in identifying genetic factors related to cognitive function in diverse populations, making this approach promising.
Where this research is happening
-
Rush University Medical Center
Chicago, United States Active
Researchers
- Principal investigator: Grodstein, Francine — Rush University Medical Center
- Study coordinator: Grodstein, Francine
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Mexican Teachers Cohort Study: Genetics and Cognitive Function
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.