Investigating genetic variations related to stroke risk and outcomes
CNV And Stroke (CaNVAS)
['FUNDING_R01'] · UNIVERSITY OF MARYLAND BALTIMORE · NIH-10746811
This study is looking at how our genes might affect the risk of having an ischemic stroke and how well people recover from it, and it’s for anyone who has had a stroke and is willing to share some health information and genetic samples to help us learn more.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MARYLAND BALTIMORE (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-10746811 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the genetic factors that contribute to ischemic stroke, which is a leading cause of death and disability. By analyzing copy number variations (CNVs) in the genomes of individuals who have experienced a stroke, the researchers aim to uncover new insights into the biological mechanisms behind stroke susceptibility and recovery. The study will utilize existing data from large genome-wide association studies (GWAS) to identify significant genetic variations that may influence stroke outcomes. Patients may be asked to provide genetic samples and health information to help in this analysis.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals aged 21 and older who have experienced an ischemic stroke.
Not a fit: Patients who have not had a stroke or are under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention strategies and treatments for ischemic stroke based on genetic insights.
How similar studies have performed: Previous research has successfully identified genetic factors in other complex diseases using similar methodologies, suggesting potential for success in this area as well.
Where this research is happening
BALTIMORE, UNITED STATES
- UNIVERSITY OF MARYLAND BALTIMORE — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: COLE, JOHN W. — UNIVERSITY OF MARYLAND BALTIMORE
- Study coordinator: COLE, JOHN W.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.