Investigating genetic risk factors for Alzheimer's disease in diverse populations
Additional Sequencing for the Alzheimer Disease Sequencing Project (ADSP) the Follow-Up Study (FUS), The Diverse Population Initiative
This study is looking at how our genes might play a role in Alzheimer's disease by analyzing DNA from a diverse group of people, especially those from different ethnic backgrounds, to help us better understand the disease and find new ways to diagnose and treat it.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-10909852 on NIH RePORTER |
What this research studies
This research focuses on identifying genetic factors that contribute to Alzheimer's disease by analyzing DNA samples from a diverse group of individuals. The project includes whole exome and whole genome sequencing of thousands of participants, particularly those from underrepresented ethnic backgrounds. By examining genetic variations and their association with Alzheimer's, the study aims to enhance our understanding of the disease and improve diagnostic and treatment strategies. Participants may contribute to a larger dataset that helps uncover novel genetic markers linked to Alzheimer's.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals of Hispanic, African, or Asian ancestry who are affected by Alzheimer's disease or related dementias.
Not a fit: Patients who do not belong to the targeted ethnic groups or who do not have Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and potential new treatments for Alzheimer's disease, particularly for diverse populations.
How similar studies have performed: Previous research initiatives focusing on genetic factors in Alzheimer's disease have shown promise, indicating that this approach could yield valuable insights.
Where this research is happening
Coral Gables, United States
- University of Miami School of Medicine — Coral Gables, United States (Active)
Researchers
- Principal investigator: Pericak-Vance, Margaret a. — University of Miami School of Medicine
- Study coordinator: Pericak-Vance, Margaret a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.