Investigating genetic factors that influence the risk of Atrial Fibrillation
Discovery and interrogation of genetic regulatory variation impacting Atrial Fibrillation risk
This study is looking at how certain genes might increase the risk of Atrial Fibrillation (AF) to help us understand the condition better and find new ways to treat it.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-11062440 on NIH RePORTER |
What this research studies
This research aims to understand how specific genetic variations contribute to the risk of Atrial Fibrillation (AF). By using advanced genomic techniques, the study will identify candidate genetic variants and their target genes that may cause AF. The researchers will analyze single-cell genomic data to gain insights into how these genetic factors interact within the heart's cells. This approach could lead to a better understanding of the molecular mechanisms behind AF and potentially inform new treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults over 21 years old who have a family history of Atrial Fibrillation or have been diagnosed with the condition.
Not a fit: Patients who are under 21 years old or do not have any genetic predisposition to Atrial Fibrillation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment options for patients at risk of Atrial Fibrillation.
How similar studies have performed: Previous research has successfully identified genetic factors associated with Atrial Fibrillation, suggesting that this approach has the potential for meaningful discoveries.
Where this research is happening
Chicago, United States
- University of Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Moskowitz, Ivan Paul — University of Chicago
- Study coordinator: Moskowitz, Ivan Paul
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.