Investigating genetic factors that influence psychiatric disorders in the human brain
Official title: SINGLE-CELL MULTI-OMIC APPROACHES TO MECHANISTICALLY CHARACTERIZE PSYCHIATRIC DISORDER RISK LOCI IN THE HUMAN BRAIN
Funded at University of California Los Angeles · NIH-11037933 · Data updated 2026-11-12
This study is looking at how certain genes might affect brain areas and cells related to mental health issues, helping us understand how our genetics can influence conditions like anxiety or depression.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | May 18, 2021 |
| Project end | February 28, 2026 |
| Funding year | 2025 |
| Award (this year) | $628,976 |
| NIH project number | 5R01MH125252-05 |
| Project ID | NIH-11037933 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adults with a history of psychiatric disorders or those at risk due to genetic factors.
✕Less likely to help
Patients without any psychiatric disorders or those who do not have a family history of such conditions may not benefit from this research.
What this research studies
This research focuses on understanding the genetic variants that contribute to psychiatric disorders by examining specific brain regions and cell types. Using advanced techniques, the study will analyze how these genetic factors interact with brain structure and function. By generating detailed datasets from various brain regions, researchers aim to identify the regulatory mechanisms that underlie these disorders. This approach will help clarify the relationship between genetic variations and their effects on mental health.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for individuals with psychiatric disorders.
How similar studies have gone: Previous research has shown promise in using genetic analysis to understand psychiatric disorders, indicating that this approach could yield valuable insights.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Luo, Chongyuan — University of California Los Angeles
- Study coordinator: Luo, Chongyuan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.