Investigating genetic factors that influence inflammatory bowel disease.
Using molecular quantitative trait loci mapping approaches to determine candidate gene regulatory mechanisms of functional variants within inflammatory bowel disease GWAS loci.
['FUNDING_FELLOWSHIP'] · UNIV OF NORTH CAROLINA CHAPEL HILL · NIH-11041000
This study is looking at how our genes might play a role in inflammatory bowel diseases like Crohn’s and ulcerative colitis, with the hope of finding better treatments by connecting genetic information to the way these diseases show up in patients.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIV OF NORTH CAROLINA CHAPEL HILL (nih funded) |
| Locations | 1 site (CHAPEL HILL, UNITED STATES) |
| Trial ID | NIH-11041000 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the genetic mechanisms behind inflammatory bowel diseases (IBD) like Crohn’s disease and ulcerative colitis. By using advanced molecular mapping techniques, the study aims to identify how specific genetic variants affect gene regulation and contribute to the disease. The approach involves analyzing genetic data from patients to uncover the underlying causes of IBD, which could lead to more effective treatments. Patients' genetic information will be linked to their disease characteristics to better understand the role of genetics in IBD.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with inflammatory bowel diseases, such as Crohn’s disease or ulcerative colitis.
Not a fit: Patients without a diagnosis of inflammatory bowel disease or those with other unrelated gastrointestinal conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to targeted therapies that address the root causes of inflammatory bowel disease rather than just managing symptoms.
How similar studies have performed: Previous research using similar genetic mapping approaches has shown promise in identifying disease mechanisms, suggesting that this study could build on established methodologies.
Where this research is happening
CHAPEL HILL, UNITED STATES
- UNIV OF NORTH CAROLINA CHAPEL HILL — CHAPEL HILL, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: NISHIYAMA, NINA — UNIV OF NORTH CAROLINA CHAPEL HILL
- Study coordinator: NISHIYAMA, NINA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.