Investigating genetic factors that contribute to obesity and its health impacts
From Obesity GWAS to therapeutic targets
This study is looking at how our genes might play a role in obesity and related health issues like type 2 diabetes and heart disease, with the hope of finding new ways to help manage weight and improve health for people struggling with obesity.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10932682 on NIH RePORTER |
What this research studies
This research focuses on understanding how genetic variations influence obesity and its associated health risks, such as type 2 diabetes and heart disease. By analyzing genetic data from various studies, the researchers aim to identify specific genetic markers linked to obesity. They will utilize advanced techniques like CRISPR and ATAC sequencing to explore how these genetic factors affect brain regions involved in appetite and weight regulation. This could lead to new therapeutic strategies for managing obesity.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with a genetic predisposition to obesity or those struggling with weight management.
Not a fit: Patients who are not affected by obesity or do not have a family history of obesity-related conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to targeted therapies that help prevent or treat obesity and its related health conditions.
How similar studies have performed: Previous research has shown promising results in identifying genetic factors related to obesity, suggesting that this approach could yield valuable insights.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Vaisse, Christian — University of California, San Francisco
- Study coordinator: Vaisse, Christian
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.