Investigating genetic factors that affect human health and disease through advanced DNA sequencing.

HIGH THROUGHPUT GENOTYPING AND DNA SEQUENCING FOR STUDYING THE GENETIC CONTRIBUTIONS TO HUMAN HEALTH AND DISEASE -WHOLE EXOME SEQUENCING (SALIVA); WHOLE GENOME SEQUENCING UPGRADE FOR NCI

NIH-funded research Johns Hopkins University · NIH-11220048

This study is looking at how your genes, found in saliva samples, might affect your health and risk for certain diseases, so we can better understand and manage inherited health conditions.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11220048 on NIH RePORTER

What this research studies

This research focuses on using high-throughput genotyping and DNA sequencing techniques to identify genetic factors that contribute to various health conditions. By analyzing saliva samples, researchers aim to uncover genetic variations that may influence disease susceptibility and health outcomes. The study employs advanced statistical genetics methods to interpret the data, providing insights that could lead to improved understanding and management of inherited diseases.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals with a family history of inherited diseases or those interested in understanding their genetic health risks.

Not a fit: Patients without any known genetic disorders or those not interested in genetic testing may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better identification of genetic risks and more personalized treatment options for patients.

How similar studies have performed: Previous research using high-throughput sequencing has shown significant success in identifying genetic contributions to various diseases, indicating a strong potential for this approach.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions DiseaseDisorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.