Investigating genetic factors related to stillbirth
Inherited and de novo genetic variants relevant to familial, recurrent and sporadic stillbirth
This study is looking at the genetic reasons behind stillbirths to help families understand what might have happened and to find ways to prevent it in the future, by analyzing DNA from parents and their stillborn babies.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project ID | NIH-11095970 on NIH RePORTER |
What this research studies
This research focuses on understanding the genetic causes of stillbirth, which affects many families worldwide. By analyzing DNA from parents and their stillborn children, the study aims to identify inherited and new genetic variants that may contribute to this tragic outcome. The approach includes advanced techniques like whole-exome and whole-genome sequencing to uncover potential genetic abnormalities. The goal is to provide insights that could help prevent future stillbirths and improve care for affected families.
Who could benefit from this research
Good fit: Ideal candidates for this research include families who have experienced stillbirth, particularly those with a history of recurrent stillbirths or unexplained cases.
Not a fit: Patients who have not experienced stillbirth or have no family history of the condition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and prevention of stillbirth, ultimately reducing its occurrence and the emotional burden on families.
How similar studies have performed: Previous research has shown promise in identifying genetic factors related to stillbirth, suggesting that this approach could yield valuable insights.
Where this research is happening
Salt Lake City, United States
- University of Utah — Salt Lake City, United States (Active)
Researchers
- Principal investigator: Workalemahu, Tsegaselassie — University of Utah
- Study coordinator: Workalemahu, Tsegaselassie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.