Investigating genetic factors of Alzheimer's disease in Jewish and Arab populations
Official title: Genetic Studies of Alzheimer's Disease in Jewish and Arab Populations
Funded at Boston University Medical Campus · NIH-10914777 · Data updated 2026-11-12
This study is looking at the genes that might contribute to Alzheimer's disease in Jewish and Arab people in Israel, hoping to find unique genetic clues that could help us understand the disease better and improve care for these communities.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $3,067,892 |
| NIH project number | 5U01AG081230-02 |
| Project ID | NIH-10914777 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation are individuals of Jewish or Arab descent living in Israel, particularly those with a family history of Alzheimer's disease.
✕Less likely to help
Patients who do not belong to the Jewish or Arab populations in Israel may not benefit from this research.
What this research studies
This research focuses on understanding the genetic basis of Alzheimer's disease (AD) specifically in Jewish and Arab populations living in Israel. By studying these genetically distinct groups, the research aims to identify unique genetic variants associated with AD that may not be present in European populations. The approach involves analyzing genetic data from a smaller, more homogeneous cohort, which can lead to the discovery of novel risk factors for Alzheimer's. This study will also consider the environmental and lifestyle factors that may influence genetic risk for AD in these populations.
Why it matters
Potential benefit: If successful, this research could lead to the identification of new genetic markers for Alzheimer's disease, improving risk assessment and potential treatment strategies for affected individuals.
How similar studies have gone: Previous research has successfully identified genetic variants associated with Alzheimer's disease in non-European populations, suggesting that this approach has potential for uncovering new insights.
Where this research is happening
-
Boston University Medical Campus
Boston, United States Active
Researchers
- Principal investigator: Farrer, Lindsay a. — Boston University Medical Campus
- Study coordinator: Farrer, Lindsay a.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.