Investigating genetic factors linked to hearing loss.
Official title: Functional Analysis of GWAS loci associated with hearing loss.
Funded at Oklahoma Medical Research Foundation · NIH-10731757 · Data updated 2026-11-12
This study is looking at how certain genes might cause hearing loss, which affects many people, to help find better ways to diagnose and treat the condition.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oklahoma Medical Research Foundation NIH-funded |
| Lab location | 1 site (Oklahoma City, United States) |
| Project start | December 1, 2022 |
| Project end | November 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $213,125 |
| NIH project number | 5R21DC020317-02 |
| Project ID | NIH-10731757 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adults experiencing hearing loss, particularly those with a suspected genetic component.
✕Less likely to help
Patients with hearing loss due to non-genetic factors, such as noise exposure or infections, may not benefit from this research.
What this research studies
This research focuses on understanding the genetic basis of hearing loss, a condition that affects millions worldwide. By analyzing specific genetic variants identified through genome-wide association studies (GWAS), the research aims to determine how these variants influence hearing function. The study will utilize advanced sequencing technologies and animal models to explore the relationship between identified genes and hearing loss phenotypes, which could lead to improved diagnostic methods and treatment options for patients.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of hearing loss, potentially improving the quality of life for affected individuals.
How similar studies have gone: Previous research utilizing GWAS approaches has successfully identified genetic factors in other conditions, suggesting a promising avenue for understanding hearing loss.
Where this research is happening
-
Oklahoma Medical Research Foundation
Oklahoma City, United States Active
Researchers
- Principal investigator: Varshney, Gaurav K — Oklahoma Medical Research Foundation
- Study coordinator: Varshney, Gaurav K
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.