Investigating genetic factors influencing breast cancer risk in Latin American women
Official title: Latin America Genomics of Breast Cancer Risk Study (LAGENO-BCR)
Funded at University of California at Davis · NIH-10981537 · Data updated 2026-11-12
This study is looking at how genetics might affect breast cancer risk in Hispanic and Latina women by comparing DNA from those with breast cancer and those without, to help improve understanding and prediction of breast cancer for these communities.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $872,878 |
| NIH project number | 1R01CA286650-01A1 |
| Project ID | NIH-10981537 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are Hispanic and Latina women, particularly those with a family history of breast cancer or those who have been diagnosed with the disease.
✕Less likely to help
Patients who do not identify as Hispanic or Latina or those who do not have a family history of breast cancer may not benefit from this research.
What this research studies
This research focuses on understanding the genetic factors that contribute to breast cancer risk specifically in Hispanic and Latina women. By analyzing DNA from a large group of breast cancer patients and unaffected women across Latin America and the U.S., the study aims to identify unique genetic variants that may influence breast cancer susceptibility. The approach involves genome-wide association studies (GWAS) to enhance the predictive accuracy of breast cancer risk models, taking into account the diverse ancestry of participants. This research seeks to fill the gap in representation of Hispanic/Latina women in genomic studies, which have predominantly focused on European populations.
Why it matters
Potential benefit: If successful, this research could lead to more accurate breast cancer risk assessments and personalized prevention strategies for Hispanic and Latina women.
How similar studies have gone: Previous research has shown success in identifying genetic variants in diverse populations, indicating that this approach could yield valuable insights for breast cancer risk in underrepresented groups.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Fejerman, Laura — University of California at Davis
- Study coordinator: Fejerman, Laura
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.