Investigating genetic factors in obesity-related asthma in children
Official title: Relevance of RPS27L expression quantitative trait locus in pediatric obesity-related asthma
Funded at Albert Einstein College of Medicine · NIH-10735895 · Data updated 2026-11-12
This study is looking at how genes might play a role in asthma related to obesity in Hispanic and African American kids, with the hope of finding ways to prevent and treat this condition by examining their blood samples.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albert Einstein College of Medicine NIH-funded |
| Lab location | 1 site (Bronx, United States) |
| Project start | November 7, 2022 |
| Project end | October 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $210,000 |
| NIH project number | 5R21AI166744-03 |
| Project ID | NIH-10735895 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children, particularly Hispanic and African American, who are overweight or obese and have been diagnosed with asthma.
✕Less likely to help
Patients who are not overweight or obese and do not have asthma may not benefit from this research.
What this research studies
This research focuses on understanding how genetic factors contribute to obesity-related asthma, particularly in Hispanic and African American children. It aims to identify genetic risk markers that could help in the primary prevention of this condition, which is increasingly prevalent among overweight children. The study examines immune responses and biological mechanisms that may lead to asthma symptoms, with the goal of discovering new therapeutic targets for treatment. By analyzing blood samples, researchers will explore the relationship between genetic variants and immune responses in children affected by obesity-related asthma.
Why it matters
Potential benefit: If successful, this research could lead to better prevention strategies and targeted treatments for obesity-related asthma in children.
How similar studies have gone: Previous research has shown promising results in identifying genetic factors related to asthma, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Albert Einstein College of Medicine
Bronx, United States Active
Researchers
- Principal investigator: Rastogi, Deepa — Albert Einstein College of Medicine
- Study coordinator: Rastogi, Deepa
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.