Investigating genetic factors in lung cancer among African Americans
CIDR: SEQUENCING SERVICES USING WHOLE GENOME SEQUENCING FOR NCI (AMOS),
This study is looking at the genes that might make some African Americans more likely to get lung cancer, especially those with a family history of the disease, to help us find new ways to understand and assess their risk.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10949101 on NIH RePORTER |
What this research studies
This research focuses on understanding the genetic factors that contribute to lung cancer, particularly in African Americans who experience higher rates of incidence and mortality. By utilizing whole genome sequencing, the study aims to identify rare genetic variants that may increase the risk of familial lung cancer in this population. The approach includes analyzing data from high-risk families and comparing it with existing genomic data from African populations to uncover unique genetic markers. This comprehensive analysis seeks to enhance our understanding of lung cancer genetics and improve risk assessment.
Who could benefit from this research
Good fit: Ideal candidates for this research are African American individuals with a family history of lung cancer.
Not a fit: Patients without a family history of lung cancer or those from other racial/ethnic backgrounds may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better identification of genetic risk factors for lung cancer in African Americans, potentially improving prevention and treatment strategies.
How similar studies have performed: While there have been successful studies on lung cancer genetics in other populations, this specific focus on African Americans and familial lung cancer is novel and has not been extensively explored.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Doheny, Kimberly F — Johns Hopkins University
- Study coordinator: Doheny, Kimberly F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.