Investigating genetic factors in Alzheimer's disease among diverse populations
South Texas Alzheimer's Disease Center Genetics and Multiomics Core
['FUNDING_P30'] · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · NIH-10880647
This study is looking at how genes and biology play a role in Alzheimer's disease, especially in Mexican American communities, to find new ways to prevent and treat dementia that fit different people's needs.
Quick facts
| Phase | ['FUNDING_P30'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TEXAS HLTH SCIENCE CENTER (nih funded) |
| Locations | 1 site (SAN ANTONIO, UNITED STATES) |
| Trial ID | NIH-10880647 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the genetic and biological factors that contribute to Alzheimer's disease and related dementias, particularly in Mexican American populations. By utilizing genome-wide association studies and multiomic approaches, the project aims to identify genetic variations that increase the risk of dementia. Participants will undergo clinical sequencing and genetic counseling to help uncover novel genetic variations. The goal is to develop more precise prevention and treatment strategies tailored to diverse populations affected by Alzheimer's disease.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a family history of Alzheimer's disease or related dementias, particularly those from Mexican American backgrounds.
Not a fit: Patients without a family history of Alzheimer's disease or those not belonging to the targeted demographic may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective prevention and treatment options for Alzheimer's disease.
How similar studies have performed: Previous research has shown success in identifying genetic factors in Alzheimer's disease, but this study aims to address gaps in data for underrepresented populations, making it a novel approach.
Where this research is happening
SAN ANTONIO, UNITED STATES
- UNIVERSITY OF TEXAS HLTH SCIENCE CENTER — SAN ANTONIO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SESHADRI, SUDHA — UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
- Study coordinator: SESHADRI, SUDHA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.