Investigating genetic factors in Alzheimer's disease among Asian populations
Official title: Project 1: Genetic Analysis
Funded at University of Pennsylvania · NIH-10878685 · Data updated 2026-11-12
This study is looking at how genes might affect the risk of Alzheimer's disease in Asian communities, hoping to find new clues that could help us understand the condition better and improve care for everyone.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $539,772 |
| NIH project number | 5U19AG079774-02 |
| Project ID | NIH-10878685 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals of Asian descent who may be at risk for Alzheimer's disease or are interested in understanding their genetic predisposition.
✕Less likely to help
Patients who do not have Asian ancestry or those who are not at risk for Alzheimer's disease may not benefit from this research.
What this research studies
This research focuses on understanding the genetic components that contribute to Alzheimer's disease (AD) specifically in Asian populations. By analyzing genetic variants and plasma biomarkers, the study aims to identify both risk and protective factors for AD. The research will utilize a comprehensive approach, comparing findings from Asian participants with existing data from other ethnic groups to uncover novel insights. This is the first major genetic study of Alzheimer's in Asian cohorts in the US and Canada, aiming to fill gaps in current knowledge.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments and risk reduction strategies for Alzheimer's disease in Asian populations.
How similar studies have gone: Previous research has shown success in genetic studies of Alzheimer's disease in other populations, but this approach focusing on Asian cohorts is novel.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Jun, Gyungah — University of Pennsylvania
- Study coordinator: Jun, Gyungah
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.