Investigating genetic factors for Alzheimer's disease in diverse populations
Functional genomic studies in diverse populations to characterize risk loci for Alzheimer Disease
This study is looking at how our genes might affect the risk of Alzheimer's disease, especially in African American and Hispanic communities, to help find better ways to prevent and treat the condition for everyone.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-10872131 on NIH RePORTER |
What this research studies
This research focuses on understanding the genetic factors that contribute to Alzheimer's disease, particularly in diverse populations such as African Americans and Hispanics. By utilizing advanced genomic techniques, the study aims to map the regulatory architecture of the genome in these populations, which has been largely overlooked in previous research. The approach includes Genome Wide Association Studies (GWAS) to identify genetic regions associated with Alzheimer's risk and to explore how these regions function at a molecular level. Patients may benefit from insights that could lead to more personalized prevention and treatment strategies for Alzheimer's disease.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals of African American or Hispanic descent who may be at risk for Alzheimer's disease.
Not a fit: Patients who do not belong to diverse populations or those who are not at risk for Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of Alzheimer's disease risk in diverse populations.
How similar studies have performed: Previous studies have shown success in identifying genetic factors for Alzheimer's disease, but this research aims to fill a critical gap by focusing on underrepresented populations.
Where this research is happening
Coral Gables, United States
- University of Miami School of Medicine — Coral Gables, United States (Active)
Researchers
- Principal investigator: Vance, Jeffery Marvin — University of Miami School of Medicine
- Study coordinator: Vance, Jeffery Marvin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.