Investigating genetic factors affecting kidney disease in sickle cell patients

Genetic modifiers of Sickle Cell Kidney Disease

NIH-funded research University of Tennessee Health Sci Ctr · NIH-11023025

This study is looking at how your genes might affect kidney problems if you have sickle cell disease, and it's for people with this condition to help find better ways to manage and treat kidney issues in the future.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Tennessee Health Sci Ctr NIH-funded
Lab location1 site (Memphis, United States)
Project IDNIH-11023025 on NIH RePORTER

What this research studies

This research focuses on understanding how genetic variations influence the development and progression of chronic kidney disease in individuals with sickle cell disease (SCD). The project involves a five-year plan where a team will analyze genomic data from a large group of patients to identify specific genetic markers associated with kidney issues. The research aims to provide insights that could lead to better management and treatment options for patients suffering from SCD-related kidney complications.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with sickle cell disease, particularly those who are African American and may be at risk for chronic kidney disease.

Not a fit: Patients without sickle cell disease or those who do not have chronic kidney disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies and better health outcomes for patients with sickle cell disease and kidney issues.

How similar studies have performed: Previous research has shown promise in understanding genetic factors in chronic diseases, suggesting that this approach could yield valuable insights.

Where this research is happening

Memphis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.