Investigating genetic factors affecting cancer risk and outcomes in African Americans
Official title: Genetic Variation in Cancer Risk and Outcomes in African Americans
Funded at Wayne State University · NIH-11034067 · Data updated 2026-11-12
This study is looking at how genetic differences affect cancer risk and outcomes in African American communities, with the goal of finding ways to better prevent and treat cancer for those at higher risk.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wayne State University NIH-funded |
| Lab location | 1 site (Detroit, United States) |
| Project start | February 13, 2024 |
| Project end | January 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $1,860,121 |
| NIH project number | 5P01CA272239-02 |
| Project ID | NIH-11034067 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include African American individuals with a family history of cancer or those diagnosed with multiple primary cancers.
✕Less likely to help
Patients who do not identify as African American or those without a significant family history of cancer may not benefit from this research.
What this research studies
This research focuses on understanding how genetic variations influence cancer risk and outcomes specifically in African American populations. By analyzing both inherited and acquired genetic mutations, the study aims to identify high-risk individuals and improve cancer prevention and treatment strategies. The project utilizes a large cohort of African American cancer survivors to explore genetic susceptibility and address barriers to genetic testing and counseling. The ultimate goal is to enhance the clinical management of hereditary cancers in this underrepresented group.
Why it matters
Potential benefit: If successful, this research could lead to better cancer prevention strategies and personalized treatment options for African American patients.
How similar studies have gone: Previous research has shown success in identifying genetic factors in cancer risk among diverse populations, but this specific focus on African Americans is relatively novel.
Where this research is happening
-
Wayne State University
Detroit, United States Active
Researchers
- Principal investigator: Schwartz, Ann G. — Wayne State University
- Study coordinator: Schwartz, Ann G.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.