Investigating genetic differences in chronic lymphocytic leukemia among African Americans
Germline and Somatic Genomic Studies in CLL Minorities
['FUNDING_R01'] · MAYO CLINIC ROCHESTER · NIH-10881753
This study is looking at how genetics might affect chronic lymphocytic leukemia (CLL) in African American patients compared to Caucasian patients, with the hope of finding ways to improve treatment and care for those affected.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MAYO CLINIC ROCHESTER (nih funded) |
| Locations | 1 site (ROCHESTER, UNITED STATES) |
| Trial ID | NIH-10881753 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the genetic factors that contribute to chronic lymphocytic leukemia (CLL) in African American patients, who are often underrepresented in cancer studies. By comparing the genomic profiles of African American CLL patients to those of Caucasian patients, the study aims to uncover differences that may explain variations in disease severity and treatment outcomes. The research will involve collecting genetic samples and clinical data from participants to analyze these disparities. Ultimately, the goal is to enhance the understanding of CLL and improve treatment strategies for African Americans.
Who could benefit from this research
Good fit: Ideal candidates for this research are African American individuals diagnosed with chronic lymphocytic leukemia.
Not a fit: Patients who are not African American or those without a diagnosis of chronic lymphocytic leukemia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective, tailored treatments for African American patients with chronic lymphocytic leukemia.
How similar studies have performed: Previous research has shown that understanding genetic differences in cancer can lead to significant advancements in treatment, suggesting this approach has potential for success.
Where this research is happening
ROCHESTER, UNITED STATES
- MAYO CLINIC ROCHESTER — ROCHESTER, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SLAGER, SUSAN L — MAYO CLINIC ROCHESTER
- Study coordinator: SLAGER, SUSAN L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.