Investigating genetic and immune factors affecting long-term lung issues after COVID-19

Genetic and Immuno-inflammatory Drivers of Post-acute Pulmonary Sequelae of SARS-CoV-2

NIH-funded research New York University School of Medicine · NIH-11032735

This study is looking at how COVID-19 can affect your lungs even after you feel better, and it's for people who have recovered from the virus; over five years, we'll check in with you to see how your lungs are doing and what might be causing any ongoing issues.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNew York University School of Medicine NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11032735 on NIH RePORTER

What this research studies

This research aims to understand the long-term effects of COVID-19, particularly focusing on pulmonary complications that some patients experience after recovery. By establishing a cohort of over 1200 patients, the study will analyze genetic and immuno-inflammatory factors that may contribute to these post-acute sequelae. Patients will undergo various assessments, including lung function tests and imaging, over a five-year period to track changes and identify potential risk factors. The goal is to better characterize the chronic effects of COVID-19 and develop targeted interventions.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have recovered from COVID-19 but are experiencing ongoing pulmonary symptoms.

Not a fit: Patients who have not been infected with SARS-CoV-2 or those without any post-acute pulmonary symptoms may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment options for patients suffering from long-term lung complications after COVID-19.

How similar studies have performed: Other research has shown promising results in understanding post-viral syndromes, but this specific approach focusing on genetic and immunological factors in COVID-19 is relatively novel.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acute Diseaseacute disease/disorderacute disorderacute infectionacute phase of SARS-CoV-2 infection
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.