Investigating genetic and immune factors affecting long-term lung issues after COVID-19
Official title: Genetic and Immuno-inflammatory Drivers of Post-acute Pulmonary Sequelae of SARS-CoV-2
Funded at New York University School of Medicine · NIH-11032735 · Data updated 2026-11-12
This study is looking at how COVID-19 can affect your lungs even after you feel better, and it's for people who have recovered from the virus; over five years, we'll check in with you to see how your lungs are doing and what might be causing any ongoing issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | February 5, 2023 |
| Project end | January 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $757,678 |
| NIH project number | 5R01HL163604-03 |
| Project ID | NIH-11032735 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have recovered from COVID-19 but are experiencing ongoing pulmonary symptoms.
✕Less likely to help
Patients who have not been infected with SARS-CoV-2 or those without any post-acute pulmonary symptoms may not benefit from this research.
What this research studies
This research aims to understand the long-term effects of COVID-19, particularly focusing on pulmonary complications that some patients experience after recovery. By establishing a cohort of over 1200 patients, the study will analyze genetic and immuno-inflammatory factors that may contribute to these post-acute sequelae. Patients will undergo various assessments, including lung function tests and imaging, over a five-year period to track changes and identify potential risk factors. The goal is to better characterize the chronic effects of COVID-19 and develop targeted interventions.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for patients suffering from long-term lung complications after COVID-19.
How similar studies have gone: Other research has shown promising results in understanding post-viral syndromes, but this specific approach focusing on genetic and immunological factors in COVID-19 is relatively novel.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Abramson, Steven B — New York University School of Medicine
- Study coordinator: Abramson, Steven B
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.