Investigating genetic and environmental factors in postpartum depression among diverse mothers

MomGenes Fight PPD: Expanding to Increase Participation from Diverse Ancestries

NIH-funded research Univ of North Carolina Chapel Hill · NIH-11120833

This study is looking at how genes and life experiences might affect postpartum depression in mothers from different backgrounds, especially in BIPOC communities, to help find better ways to identify and treat this condition.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill NIH-funded
Lab location1 site (Chapel Hill, United States)
Project IDNIH-11120833 on NIH RePORTER

What this research studies

This research aims to explore the genetic risk factors associated with postpartum depression (PPD) and how they interact with environmental influences, particularly focusing on mothers from diverse ancestries, including BIPOC communities. By analyzing genomic data and environmental factors such as adverse life events and discrimination, the study seeks to enhance early detection methods for PPD. The goal is to develop personalized therapies that can effectively address the unique challenges faced by these mothers. Participants will contribute to a deeper understanding of PPD, which affects many women and can have lasting impacts on their children.

Who could benefit from this research

Good fit: Ideal candidates for this research include mothers, especially those from BIPOC communities, who are experiencing or at risk for postpartum depression.

Not a fit: Patients who are not mothers or who do not have a history of postpartum depression may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved early detection and personalized treatment options for postpartum depression, particularly benefiting mothers from diverse backgrounds.

How similar studies have performed: Previous research has shown that increasing diversity in genomic studies can lead to significant advancements in understanding health disparities, suggesting that this approach has the potential for success.

Where this research is happening

Chapel Hill, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.