Investigating genetic and environmental factors in infant deaths in San Diego from 2015 to 2022
Official title: Genomic and Environmental Determinants of Infant Deaths in San Diego County in 2015-2022
Funded at Rady Pediatric Genomics & Systems Medicine Institute · NIH-10767176 · Data updated 2026-11-12
This study is looking into why some babies sadly don't survive by exploring both their genes and the environment around them, hoping to find ways to better diagnose and treat seriously ill infants in San Diego County.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rady Pediatric Genomics & Systems Medicine Institute NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project start | April 1, 2020 |
| Project end | January 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $652,671 |
| NIH project number | 5R01HD101540-05 |
| Project ID | NIH-10767176 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include infants who have experienced severe health issues or have died from unexplained causes.
✕Less likely to help
Patients who are older than 11 years or those without any genetic or environmental risk factors for infant mortality may not benefit from this research.
What this research studies
This research focuses on understanding the causes of infant mortality by examining genetic and environmental factors. By utilizing advanced genome sequencing techniques, the study aims to identify genetic diseases linked to infant deaths in San Diego County. The research will analyze data from 1,000 infant deaths between 2015 and 2022, allowing for a comprehensive evaluation of how genetics and environmental influences contribute to these tragic outcomes. The goal is to improve early diagnosis and treatment options for seriously ill infants.
Why it matters
Potential benefit: If successful, this research could lead to more effective interventions and treatments for genetic diseases in infants, ultimately reducing mortality rates.
How similar studies have gone: Previous studies have shown success in using genomic medicine to diagnose genetic conditions in seriously ill infants, indicating a promising approach for this research.
Where this research is happening
-
Rady Pediatric Genomics & Systems Medicine Institute
San Diego, United States Active
Researchers
- Principal investigator: Kingsmore, Stephen Francis — Rady Pediatric Genomics & Systems Medicine Institute
- Study coordinator: Kingsmore, Stephen Francis
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.