Investigating genetic and environmental factors in diabetes complications
Official title: Genomic, gene-environment and casual inference studies in diabetic complications
Funded at University of California, San Diego · NIH-11086777 · Data updated 2026-11-12
This study is looking at how your genes and the environment around you can affect the complications that come with type 2 diabetes, and it invites patients to share their health information and genetic samples to help find out more about this important connection.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | July 15, 2023 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $539,776 |
| NIH project number | 5R01DK135868-03 |
| Project ID | NIH-11086777 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with type 2 diabetes, particularly those experiencing complications or at high risk for them.
✕Less likely to help
Patients without a diagnosis of type 2 diabetes or those who do not have any complications related to diabetes may not benefit from this research.
What this research studies
This research focuses on understanding how genetic and environmental factors contribute to complications arising from type 2 diabetes. By analyzing large samples of patients, the study aims to identify specific genes and biological pathways that increase the risk of complications such as organ damage. The research will also explore how these genetic factors interact with environmental influences, providing a comprehensive view of diabetes complications. Patients may be involved in providing genetic samples and health information to help uncover these critical insights.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for diabetes complications, ultimately enhancing patient outcomes.
How similar studies have gone: Previous research has shown promise in identifying genetic factors related to diabetes complications, indicating that this approach could yield valuable insights.
Where this research is happening
-
University of California, San Diego
La Jolla, United States Active
Researchers
- Principal investigator: Salem, Rany — University of California, San Diego
- Study coordinator: Salem, Rany
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.