Investigating genes that regulate aging and related diseases in veterans
BLRD Research Career Scientist Award Application
This study is looking at how certain genes, SIRT6 and SIRT7, might affect aging and related health issues like heart disease, diabetes, and cancer in veterans who are 65 and older, with the goal of finding new ways to help them stay healthier as they age.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Admin Palo Alto Health Care Sys NIH-funded |
| Lab location | 1 site (Palo Alto, United States) |
| Project ID | NIH-11103206 on NIH RePORTER |
What this research studies
This research focuses on understanding how specific genes, SIRT6 and SIRT7, influence the aging process and its associated diseases, particularly in veterans aged 65 and older. By examining how these genes affect conditions like cardiovascular disease, diabetes, and cancer, the research aims to uncover potential therapeutic targets that could improve health outcomes. The approach involves studying the biological mechanisms of aging and how gene activity can be modified to protect against age-related pathologies. This work is crucial as it addresses the health needs of an aging veteran population, which is expected to grow significantly in the coming years.
Who could benefit from this research
Good fit: Ideal candidates for this research are veterans aged 65 and older who may be experiencing age-related health issues.
Not a fit: Patients under the age of 65 or those without age-related diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that improve health and quality of life for aging veterans.
How similar studies have performed: Previous research has shown promise in targeting aging-related genes for therapeutic interventions, indicating potential success for this approach.
Where this research is happening
Palo Alto, United States
- Veterans Admin Palo Alto Health Care Sys — Palo Alto, United States (Active)
Researchers
- Principal investigator: Chua, Katrin F — Veterans Admin Palo Alto Health Care Sys
- Study coordinator: Chua, Katrin F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.