Investigating genes linked to smoking in head and neck cancer in Appalachia
Evaluation of smoking-associated genes in disparate Appalachian head and neck cancer
This study is looking at how certain genes might affect why smokers in the Appalachian region often have more advanced head and neck cancer, with the hope of finding new ways to help improve their treatment and survival.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | West Virginia University NIH-funded |
| Lab location | 1 site (Morgantown, United States) |
| Project ID | NIH-10863886 on NIH RePORTER |
What this research studies
This research focuses on understanding the genetic factors that contribute to the high rates of late-stage head and neck cancer among smokers in the Appalachian region. By analyzing specific genes associated with smoking, the study aims to uncover the underlying mechanisms that lead to poorer survival rates in these patients. The research will utilize genomic analysis to identify both well-known and lesser-studied genes that may play a role in cancer progression. The ultimate goal is to find new therapeutic targets that could improve treatment outcomes for affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals from the Appalachian region who have been diagnosed with late-stage head and neck cancer and have a history of tobacco use.
Not a fit: Patients who do not have a history of smoking or those with early-stage head and neck cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies and better survival rates for patients with head and neck cancer linked to smoking.
How similar studies have performed: Previous research has shown promising results in identifying genetic factors associated with cancer outcomes, suggesting that this approach may yield valuable insights.
Where this research is happening
Morgantown, United States
- West Virginia University — Morgantown, United States (Active)
Researchers
- Principal investigator: Weed, Scott a — West Virginia University
- Study coordinator: Weed, Scott a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.