Investigating genes linked to neurodevelopmental disorders like autism.
Functional Studies of NDD Gene(s)
['FUNDING_R01'] · UNIVERSITY OF ALABAMA AT BIRMINGHAM · NIH-11050357
This study is looking at how certain genes might influence brain development and behavior in conditions like autism and intellectual disabilities, using specially modified mice to help find new ways to understand and treat these challenges.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ALABAMA AT BIRMINGHAM (nih funded) |
| Locations | 1 site (BIRMINGHAM, UNITED STATES) |
| Trial ID | NIH-11050357 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the genetic causes of neurodevelopmental disorders, particularly autism and intellectual disabilities. By using a genetically modified mouse model, researchers will explore how specific genes affect brain function and behavior. The study will involve advanced techniques such as RNA sequencing and MRI to analyze brain changes and behavior at different developmental stages. The goal is to provide insights that could lead to better understanding and treatment options for these disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with autism spectrum disorders or related neurodevelopmental conditions.
Not a fit: Patients with neurodevelopmental disorders not linked to the specific genes being studied may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic and therapeutic strategies for individuals with neurodevelopmental disorders.
How similar studies have performed: Previous research has shown promising results in understanding genetic contributions to neurodevelopmental disorders using similar methodologies.
Where this research is happening
BIRMINGHAM, UNITED STATES
- UNIVERSITY OF ALABAMA AT BIRMINGHAM — BIRMINGHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: POWELL, CRAIG M — UNIVERSITY OF ALABAMA AT BIRMINGHAM
- Study coordinator: POWELL, CRAIG M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.