Investigating Frontotemporal Lobar Degeneration and its impact on patients
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)
This study is looking at Frontotemporal Lobar Degeneration (FTLD) to learn more about what causes it and how it affects people under 65, so we can find better ways to diagnose and treat those living with this condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-10889898 on NIH RePORTER |
What this research studies
This research focuses on Frontotemporal Lobar Degeneration (FTLD), a group of neurodegenerative disorders that primarily affect individuals under 65 years of age. It aims to understand the causes of FTLD, particularly the role of toxic protein aggregates in the central nervous system. The study involves enrolling patients with both familial and sporadic forms of FTLD, tracking their progression over time to improve diagnosis and treatment options. By following these patients longitudinally, the research seeks to gather valuable data that can lead to better management strategies for those affected.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Frontotemporal Lobar Degeneration, particularly those with a family history or known genetic mutations.
Not a fit: Patients with other forms of dementia unrelated to Frontotemporal Lobar Degeneration may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic accuracy and treatment options for patients with Frontotemporal Lobar Degeneration.
How similar studies have performed: Previous research on Frontotemporal Lobar Degeneration has shown promise in understanding its genetic underpinnings and progression, indicating that this approach could yield valuable insights.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Boeve, Bradley F — Mayo Clinic Rochester
- Study coordinator: Boeve, Bradley F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.