Investigating fracture risk and bone changes in elderly men

Long term fracture risk and change in peripheral bone in the oldest old men: The MrOS study

NIH-funded research California Pacific Med Ctr Res Institute · NIH-10911380

This study is looking at how bone health changes in men aged 80 and older to help understand the risk of fractures, and it’s for older men who want to contribute to research that could improve their quality of life and help prevent broken bones.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCalifornia Pacific Med Ctr Res Institute NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-10911380 on NIH RePORTER

What this research studies

This research focuses on understanding how bone density and structure change in men aged 80 and older, particularly in relation to the risk of fractures. By following a cohort of older men over time, the study utilizes advanced imaging techniques like DXA and CT scans to assess bone health and identify risk factors for fractures. The goal is to gather comprehensive data that can inform strategies to prevent fractures and improve the quality of life for elderly men. Participants will contribute to a long-term study that aims to address critical gaps in knowledge about bone health in aging men.

Who could benefit from this research

Good fit: Ideal candidates for this research are men aged 80 and older who are at risk for bone fractures.

Not a fit: Patients who are younger than 80 or do not have concerns related to bone health may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved prevention strategies for fractures in elderly men, enhancing their independence and quality of life.

How similar studies have performed: Other studies have successfully identified risk factors for fractures in older populations, making this research a continuation of established findings in the field.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.