Investigating fracture risk and bone changes in elderly men
Official title: Long term fracture risk and change in peripheral bone in the oldest old men: The MrOS study
Funded at California Pacific Med Ctr Res Institute · NIH-10911380 · Data updated 2026-11-12
This study is looking at how bone health changes in men aged 80 and older to help understand the risk of fractures, and it’s for older men who want to contribute to research that could improve their quality of life and help prevent broken bones.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | California Pacific Med Ctr Res Institute NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | September 30, 2020 |
| Project end | May 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $2,556,546 |
| NIH project number | 5R01AG066671-05 |
| Project ID | NIH-10911380 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are men aged 80 and older who are at risk for bone fractures.
✕Less likely to help
Patients who are younger than 80 or do not have concerns related to bone health may not benefit from this research.
What this research studies
This research focuses on understanding how bone density and structure change in men aged 80 and older, particularly in relation to the risk of fractures. By following a cohort of older men over time, the study utilizes advanced imaging techniques like DXA and CT scans to assess bone health and identify risk factors for fractures. The goal is to gather comprehensive data that can inform strategies to prevent fractures and improve the quality of life for elderly men. Participants will contribute to a long-term study that aims to address critical gaps in knowledge about bone health in aging men.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention strategies for fractures in elderly men, enhancing their independence and quality of life.
How similar studies have gone: Other studies have successfully identified risk factors for fractures in older populations, making this research a continuation of established findings in the field.
Where this research is happening
-
California Pacific Med Ctr Res Institute
San Francisco, United States Active
Researchers
- Principal investigator: Cawthon, Peggy Mannen — California Pacific Med Ctr Res Institute
- Study coordinator: Cawthon, Peggy Mannen
Related research
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Next-Generation MRI to Predict Bone Healing Using Virtual Testing
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.