Investigating fluid-based biomarkers for various biological processes
Core E: Omics Core
['FUNDING_OTHER'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-10667582
This study is looking for volunteers to help us find important markers in blood and spinal fluid that could help us understand diseases like Alzheimer's better, so we can improve health for everyone.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded) |
| Locations | 1 site (PITTSBURGH, UNITED STATES) |
| Trial ID | NIH-10667582 on ClinicalTrials.gov |
What this research studies
This research focuses on the advanced quantitation of biomarkers found in blood and cerebrospinal fluid to understand various biological processes from the genome to the metabolome. By collecting samples from participants, the team will analyze genomic, transcriptomic, proteomic, and metabolomic data to identify potential biomarkers for conditions like Alzheimer's disease. The study employs both targeted and untargeted methods to ensure a comprehensive analysis, aiming to create a rich dataset that can be shared with the scientific community for further research. Participants will contribute to a clinical protocol that seeks to enhance our understanding of these biomarkers and their implications for health.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals with neurological conditions or those at risk for such conditions, particularly Alzheimer's disease.
Not a fit: Patients with conditions unrelated to neurological disorders may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the discovery of new biomarkers that improve diagnosis and treatment for neurological disorders.
How similar studies have performed: Previous research has shown promise in using fluid-based biomarkers for diagnosing and monitoring neurological conditions, indicating that this approach has potential for success.
Where this research is happening
PITTSBURGH, UNITED STATES
- UNIVERSITY OF PITTSBURGH AT PITTSBURGH — PITTSBURGH, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: O'BRYANT, SID E — UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- Study coordinator: O'BRYANT, SID E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.