Investigating fat tissue and inflammation related to heart disease in people with HIV in Uganda
Official title: Pericoronary Adipose Tissue, Inflammation, and Subclinical Coronary Artery Disease in People with HIV in Uganda
Funded at Mbarara University/science/ Technology · NIH-10999332 · Data updated 2026-11-12
This study is looking at how fat around the heart and inflammation might affect the risk of heart disease in people living with HIV in Uganda, and it hopes to find a new way to spot early signs of heart problems that regular tests might miss.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mbarara University/science/ Technology NIH-funded |
| Lab location | 1 site (Mbarara, Uganda) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $99,384 |
| NIH project number | 1K43TW012846-01 |
| Project ID | NIH-10999332 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals living with HIV in Uganda who may be at risk for coronary artery disease.
✕Less likely to help
Patients who do not have HIV or those who are not located in Uganda may not benefit from this research.
What this research studies
This research focuses on understanding how pericoronary adipose tissue (fat around the coronary arteries) and inflammation contribute to the risk of coronary artery disease (CAD) in individuals living with HIV in Uganda. The study aims to evaluate whether this fat tissue can be used as a new imaging technique to detect early signs of heart disease that are often missed by standard methods. The principal investigator, Dr. Prossy Bibangambah, will receive training in advanced imaging and statistical methods to enhance her skills in this area. By exploring these connections, the research seeks to improve early detection and treatment strategies for heart disease in this population.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and better management of heart disease in people living with HIV.
How similar studies have gone: While the approach of using pericoronary adipose tissue for early detection of heart disease is innovative, similar studies have shown promise in other populations, indicating potential for success.
Where this research is happening
-
Mbarara University/science/ Technology
Mbarara, Uganda Active
Researchers
- Principal investigator: Bibangambah, Prossy Kyasimire — Mbarara University/science/ Technology
- Study coordinator: Bibangambah, Prossy Kyasimire
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.