Investigating factors that lead to early-onset colorectal cancer.

PROSPECT - Microbiome Studies. (PATHWAYS, RISK FACTORS, AND MOLECULES TO PREVENT EARLY-ONSET COLORECTAL TUMOURS)

NIH-funded research University of Trento · NIH-11042285

This study is looking into what causes colorectal cancer in people under 50, using animal models and data to find out how biology, environment, and lifestyle play a role, so we can come up with better ways to prevent this disease and help those at risk.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Trento NIH-funded
Lab location1 site (Trento, Italy)
Project IDNIH-11042285 on NIH RePORTER

What this research studies

This research aims to understand the complex factors that contribute to colorectal cancer in individuals under 50 years old. By examining biological, environmental, and lifestyle influences, the team will utilize advanced animal models and data analysis to identify key risk factors. The goal is to develop strategies for prevention and interception of this disease, ultimately aiming to reverse the rising trend of early-onset colorectal cancer. Patients may benefit from insights that could lead to new prevention methods tailored to their specific risk profiles.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals under 50 years old who may be at risk for colorectal cancer due to genetic, environmental, or lifestyle factors.

Not a fit: Patients over the age of 50 or those with established colorectal cancer may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to effective prevention strategies for early-onset colorectal cancer, potentially saving lives.

How similar studies have performed: Previous research has shown promise in understanding the microbiome's role in cancer prevention, making this approach both relevant and potentially impactful.

Where this research is happening

Trento, Italy

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.