Investigating factors affecting the accuracy of diagnostic tests for certain types of blood cancers
Pre-analytical variables of bioanalytes affecting the accuracy of PTCL diagnostic and prognostic genetic signatures
This study is working on making tests for peripheral T-cell lymphomas more accurate by looking at genetic information from patients, which will help doctors better understand the different types of this cancer and improve treatment options for patients.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nebraska Medical Center NIH-funded |
| Lab location | 1 site (Omaha, United States) |
| Project ID | NIH-10903746 on NIH RePORTER |
What this research studies
This research focuses on improving the accuracy of diagnostic tests for peripheral T-cell lymphomas (PTCL), which are challenging to diagnose and often have poor outcomes. The team is developing genetic signatures that can differentiate between various subtypes of PTCL, using advanced techniques to analyze both RNA and DNA from patient samples. By examining how pre-analytical variables affect these bioanalytes, the research aims to enhance the reliability of diagnostic tests, ultimately aiding in better patient management and treatment decisions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with peripheral T-cell lymphomas or those suspected of having these conditions.
Not a fit: Patients with other types of lymphomas or blood cancers that are not peripheral T-cell lymphomas may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and improved prognostic assessments for patients with peripheral T-cell lymphomas.
How similar studies have performed: Previous research has shown promise in using genetic signatures for diagnosing various cancers, suggesting that this approach may yield successful outcomes.
Where this research is happening
Omaha, United States
- University of Nebraska Medical Center — Omaha, United States (Active)
Researchers
- Principal investigator: Iqbal, Javeed — University of Nebraska Medical Center
- Study coordinator: Iqbal, Javeed
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.