Investigating factors affecting tests for congenital syphilis
Pre-Analytic Factors affecting Molecular tests for Congenital Syphilis
['FUNDING_R21'] · UT SOUTHWESTERN MEDICAL CENTER · NIH-10977800
This study is looking at how different factors can affect tests for congenital syphilis in newborns, with the goal of creating better and more accurate ways to detect the infection so that pregnant people and their babies can get the right treatment.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UT SOUTHWESTERN MEDICAL CENTER (nih funded) |
| Locations | 1 site (DALLAS, UNITED STATES) |
| Trial ID | NIH-10977800 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the pre-analytic factors that influence molecular tests for congenital syphilis, a serious condition affecting newborns. The study aims to develop accurate and sensitive diagnostic methods using polymerase chain reaction (PCR) techniques, which can directly detect syphilis infection. By improving diagnostic accuracy, the research seeks to enhance treatment decisions for affected neonates and pregnant individuals. The approach involves analyzing various factors that may impact test results to ensure reliable detection of the infection.
Who could benefit from this research
Good fit: Ideal candidates for this research include pregnant individuals at risk for syphilis and their newborns, particularly those showing symptoms or with a history of maternal syphilis.
Not a fit: Patients who are not pregnant or do not have a risk of syphilis infection may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and timely diagnoses of congenital syphilis, ultimately improving health outcomes for newborns and pregnant individuals.
How similar studies have performed: Previous research has shown success with PCR-based diagnostic methods for other infectious diseases, indicating potential for similar advancements in congenital syphilis detection.
Where this research is happening
DALLAS, UNITED STATES
- UT SOUTHWESTERN MEDICAL CENTER — DALLAS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SORELLE, JEFFREY — UT SOUTHWESTERN MEDICAL CENTER
- Study coordinator: SORELLE, JEFFREY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.