Investigating factors affecting brain health in elderly individuals with Alzheimer's Disease
Predictors of Altered CNS Structure, Function, and Connectomics in the Elderly using a Health Disparities Framework
This study is looking at how different social and environmental factors, especially related to race, affect the development of Alzheimer's Disease in older adults, and it involves brain scans and personal information from a diverse group of participants to help us understand these connections better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-10762430 on NIH RePORTER |
What this research studies
This research aims to explore how structural and social determinants influence the development of Alzheimer's Disease (AD) in elderly individuals, particularly focusing on racial disparities. By utilizing a diverse sample from the Human Connectome Project, the study will assess both biological and environmental factors that contribute to cognitive impairments. Participants will undergo brain imaging and provide demographic and behavioral data over multiple visits to better understand the interplay between health equity and cognitive dysfunction in aging populations.
Who could benefit from this research
Good fit: Ideal candidates for this research are elderly individuals, particularly those from diverse racial backgrounds, who may be at risk for Alzheimer's Disease.
Not a fit: Patients who are not elderly or do not have concerns related to Alzheimer's Disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and interventions for Alzheimer's Disease, particularly in addressing health disparities among different racial groups.
How similar studies have performed: Previous research has shown success in understanding health disparities in cognitive decline, but this specific approach utilizing a health equity framework is relatively novel.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Cohen, Ann D. — University of Pittsburgh at Pittsburgh
- Study coordinator: Cohen, Ann D.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.