Investigating extracellular vesicles and their RNA for health and disease insights
Official title: BLRD Research Career Scientist Award Application
Funded at Veterans Affairs Med Ctr San Francisco · NIH-11103172 · Data updated 2026-11-12
This study is looking at tiny particles in the body called extracellular vesicles to see if they can help us understand and improve health issues, especially for Veterans with heart and inflammation problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Affairs Med Ctr San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | April 1, 2021 |
| Project end | March 31, 2026 |
| Funding year | 2025 |
| NIH project number | 5IK6BX005692-05 |
| Project ID | NIH-11103172 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include Veterans with advanced vascular disease or those experiencing inflammation-related health issues.
✕Less likely to help
Patients without vascular disease or those not affected by inflammation may not benefit from this research.
What this research studies
This research focuses on understanding extracellular vesicles (EVs) and their RNA content as potential biomarkers for various health conditions, particularly in Veterans. The project aims to develop innovative methods to study these vesicles and their role in inflammation and cardiovascular diseases. By examining how EVs influence intercellular communication and disease progression, the research seeks to identify new therapeutic targets and biomarkers. Patients may benefit from insights gained through this research, particularly those with advanced vascular diseases.
Why it matters
Potential benefit: If successful, this research could lead to new biomarkers and therapies for managing cardiovascular diseases and inflammation.
How similar studies have gone: Previous research has shown promise in using extracellular vesicles as biomarkers and therapeutic agents, indicating a potential for success in this area.
Where this research is happening
-
Veterans Affairs Med Ctr San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Raffai, Robert — Veterans Affairs Med Ctr San Francisco
- Study coordinator: Raffai, Robert
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.