Investigating energy metabolism in pulmonary hypertension related to chronic lung disease
Official title: Bioenergetic impairment in Group 3 pulmonary hypertension
Funded at Emory University · NIH-10914270 · Data updated 2026-11-12
This study is looking at how energy use in blood vessels changes for people with pulmonary hypertension from chronic lung disease, and it aims to find new treatments that could help improve their health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $178,200 |
| NIH project number | 5K23HL166775-02 |
| Project ID | NIH-10914270 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who are diagnosed with pulmonary hypertension related to chronic lung disease.
✕Less likely to help
Patients with pulmonary hypertension not related to chronic lung disease or those under 21 years of age may not benefit from this research.
What this research studies
This research focuses on understanding how energy metabolism in blood vessels is altered in patients with pulmonary hypertension caused by chronic lung disease. The study aims to explore the cellular changes that contribute to this condition and evaluate new treatment strategies that target these metabolic pathways. By analyzing human samples and conducting clinical trials, the research seeks to identify effective interventions that could improve patient outcomes. The principal investigator is dedicated to advancing knowledge in this area and developing novel therapies for affected patients.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options that significantly improve the quality of life and survival rates for patients with pulmonary hypertension due to chronic lung disease.
How similar studies have gone: Previous research has shown promising results in targeting metabolic pathways in pulmonary hypertension, indicating that this approach may lead to significant advancements in treatment.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Trammell, Aaron Wayne — Emory University
- Study coordinator: Trammell, Aaron Wayne
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.